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Chemical Structure : Lalistat-1
CAS No.: 501104-16-1
Catalog No.: PC-20890Not For Human Use, Lab Use Only.
Lalistat 1 is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase.
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|---|---|---|---|
| 5 mg | $188 | In stock | |
| 25 mg | $358 | In stock | |
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Lalistat 1 is a potent and selective lysosomal acid lipase (LAL) inhibitor with IC50 of 68 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase.
Lalistat 1 interferes with neutral lipolysis.
Lalistat 1 binds to active center of neutral lipid hydrolases.
| M.Wt | 298.36 | |
| Formula | C12H18N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
O=C(OC1=NSN=C1N2CCCCC2)N3CCOCC3 |
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1. Bradić I, et al. Mol Metab. 2022 Jul;61:101510.
2. Hamilton J, et al. Clin Chim Acta. 2012 Aug 16;413(15-16):1207-10.
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