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Chemical Structure : Lalistat-2
CAS No.: 1234569-09-5
Catalog No.: PC-20889Not For Human Use, Lab Use Only.
Lalistat-2 (L-stat) is a specific inhibitor of lysosomal acid lipase (LAL) with IC50 of 152 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $188 | In stock | |
| 25 mg | $358 | In stock | |
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Lalistat-2 (L-stat) is a specific inhibitor of lysosomal acid lipase (LAL) with IC50 of 152 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase.
Lalistat 2 interferes with neutral lipolysis.
Lalistat 2 binds to active center of neutral lipid hydrolases.
| M.Wt | 296.39 | |
| Formula | C13H20N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-(1-Piperidinyl)-1,2,5-thiadiazol-3-yl 1-piperidinecarboxylate |
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1. Anton I Rosenbaum, et al. J Med Chem. 2010 Jul 22;53(14):5281-9.
2. Bradić I, et al. Mol Metab. 2022 Jul;61:101510.
3. Hamilton J, et al. Clin Chim Acta. 2012 Aug 16;413(15-16):1207-10.
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