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Chemical Structure : Larazotide acetate
CAS No.: 881851-50-9
Catalog No.: PC-49429Not For Human Use, Lab Use Only.
Larazotide acetate (AT1001) is a synthetic, competitive octapeptide inhibitor of zonulin, acts as a tight junction regulator to restore intestinal barrier function.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $198 | In stock | |
| 25 mg | $328 | In stock | |
| 100 mg | $698 | In stock | |
| 1 g | Get quote |
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Larazotide acetate (AT1001) is a synthetic, competitive octapeptide inhibitor of zonulin, acts as a tight junction regulator to restore intestinal barrier function.
Larazotide acetate specifically increases intestinal barrier integrity, effectively reduces arthritis onset.
Larazotide acetate decreases plasma SARS-CoV-2 spike antigen levels and inflammatory markers in multisystem inflammatory syndrome in children (MIS-C).
Larazotide acetate binds SARS-CoV-2 Mpro catalytic domain.
| M.Wt | 785.89 | |
| Formula | C34H59N9O12 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Glycine, glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolyl-, acetate (1:1) |
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1. Tajik N, et al. Nat Commun. 2020 Apr 24;11(1):1995.
2. Benjamin ER, et al. Mol Ther. 2012 Apr;20(4):717-26.
3. Di Micco S, et al. Int J Mol Sci. 2021 Aug 30;22(17):9427.
4. M C Arrieta, et al. Gut. 2009 Jan;58(1):41-8.
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