M9101

Chemical Structure : M9101

Catalog No.: PC-26926Not For Human Use, Lab Use Only.

M9101 is a potent, selective and in vivo active Aurora A PROTAC degrader with DC50 value of 2.3 nM in MD-MBA-231 cells.

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Biological Activity

M9101 is a potent, selective and in vivo active Aurora A PROTAC degrader with DC50 value of 2.3 nM in MD-MBA-231 cells.

M.Wt	784.29
Formula	C38H38ClN9O6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((5-chloro-2-((4-(4-(6-(2,6-dioxopiperidin-3-yl)-5,7-dioxo-3,5,6,7-tetrahydropyrrolo[3,4-f]isoindol-2(1H)-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N,N-dimethylbenzenesulfonamide

1. Yulin Mao, et al. J Med Chem. 2026 May 29. doi: 10.1021/acs.jmedchem.6c00183.