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MAC1

Chemical Structure : MAC1

CAS No.: 325970-42-1

MAC1 (Monastrol Antagonizing Compound 1)

Catalog No.: PC-62405Not For Human Use, Lab Use Only.

MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MAC1 (Monastrol Antagonizing Compound 1) is a small molecule that can rescue spindle bipolarity in cells lacking Eg5 activity.
    MAC1 induces the formation of additional microtubule nucleation centers, which allows kinesin Kif15-dependent bipolar spindle assembly in the absence of Eg5 activity.

    Physicochemical Properties

    M.Wt 247.338
    Formula C15H21NO2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-1-(1-hydroxycyclohexyl)-3-phenylpropan-1-one oxime

    References

    1. Al-Obaidi N, et al. ACS Chem Biol. 2016 Jun 17;11(6):1544-51.

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