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Chemical Structure : MAGMAS inhibitor BT9
Catalog No.: PC-21924Not For Human Use, Lab Use Only.
MAGMAS inhibitor BT9 is a small molecule MAGMAS (mitochondria associated, granulocyte-macrophage colony stimulating factor signaling molecule) inhibitor with binding Kd of 33 uM.
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MAGMAS inhibitor BT9 is a small molecule MAGMAS (mitochondria associated, granulocyte-macrophage colony stimulating factor signaling molecule) inhibitor with binding Kd of 33 uM.
MAGMAS inhibitor BT9 inhibits growth at the 4 μM scale in yeast proliferation assays.
MAGMAS inhibitor BT9 decreases cell proliferation, migration, and oxidative phosphorylation in adult glioblastoma cell lines (DAOY cell, 24hrs IC50: 3.6uM; D425 cells, 24hrs IC50: 3.4uM).
| M.Wt | 325.46 | |
| Formula | C20H27N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zahra Motahari, et al. bioRxiv. 2024 Mar 3:2024.02.29.582709.
2. Paul T Jubinsky, et al. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3479-82.
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