MAT2A inhibitor 29 | MAT2A inhibitor | Probechem Biochemicals

Chemical Structure : MAT2A inhibitor 29

Catalog No.: PC-21895Not For Human Use, Lab Use Only.

MAT2A inhibitor 29 (AZ-29) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A with IC50 of 27.9 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MAT2A inhibitor 29 (AZ-29) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A with IC50 of 27.9 nM.

M.Wt	313.79
Formula	C17H16ClN3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-chloro-4-(dimethylamino)-1-(m-tolyl)quinazolin-2(1H)-one

1. Feng Gao, et al. Bioorg Med Chem. 2024 Feb 15:100:117633.

2. Claudia De Fusco, et al. J Med Chem. 2021 May 27;64(10):6814-6826.