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MC-100093

Chemical Structure : MC-100093

CAS No.: 1639784-02-3

MC-100093 (MC100093)

Catalog No.: PC-72279Not For Human Use, Lab Use Only.

MC-100093 (MC100093) is a potent, orally bioavailable upregulator of GLT-1 and devoid of antimicrobial properties.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MC-100093 (MC100093) is a potent, orally bioavailable upregulator of GLT-1 and devoid of antimicrobial properties.
MC-100093 enhanced uptake of glutamate into astrocytes in a mouse neuron/astrocyte co-culture model with IC50 of 0.1 uM.
MC-100093 restored the expression of NA core GLT-1.
MC-100093 (50 mg/kg) attenuated cue-primed relapse to cocaine-seeking without reducing motivation to consume regular chow or sucrose pellets or affecting body weight.

Physicochemical Properties

M.Wt 269.345
Formula C13H23N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Lori A Knackstedt, et al. J Pharmacol Exp Ther. 2021 Aug;378(2):51-59.

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