MC2606

Chemical Structure : MC2606

Catalog No.: PC-25601Not For Human Use, Lab Use Only.

MC2606 is a potent, selective activator of SIRT1, MC2606 (1 uM) induces H4K16 deacetylation in HaCaT cells.

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Biological Activity

MC2606 is a potent, selective activator of SIRT1, MC2606 (1 uM) induces H4K16 deacetylation in HaCaT cells.

M.Wt	397.49
Formula	C22H23NO4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	diethyl 1-benzyl-4-(thiophen-3-yl)-1,4-dihydropyridine-3,5-dicarboxylate

1. Suenkel B, et al. J Med Chem. 2022 Oct 27;65(20):14015-14031.

2. Sergio Valente, et al. J Med Chem. 2016 Feb 25;59(4):1471-91.

3. Carola Castiello, et al. Drug Des Devel Ther. 2025 Jun 27:19:5489-5505.