MC3215

Chemical Structure : MC3215

Catalog No.: PC-25602Not For Human Use, Lab Use Only.

MC3215 is a specific, cellular active small molecule activator of mitochondrial SIRT5 with binding KD of 28 uM, increases in vitro Sirt5 deacetylase activity and elicits similar effects to Sirt5 overexpression.

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Biological Activity

Physicochemical Properties

M.Wt	411.47
Formula	C22H21NO5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	diethyl 1-benzoyl-4-(thiophen-3-yl)-1,4-dihydropyridine-3,5-dicarboxylate

References

1. Suenkel B, et al. J Med Chem. 2022 Oct 27;65(20):14015-14031.

2. Carola Castiello, et al. Drug Des Devel Ther. 2025 Jun 27:19:5489-5505.

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MC3215

Biological Activity

Physicochemical Properties

References

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