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MC3482

Chemical Structure : MC3482

CAS No.: 2922280-86-0

MC3482 (MC 3482)

Catalog No.: PC-63242Not For Human Use, Lab Use Only.

MC3482 is a potent, specific SIRT5 inhibitor, increases the ammonia content in cells leading to autophagy and mitophagy, shows selective SIRT5 inhibition vs SIRT1-3..

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    Biological Activity

    MC3482 is a potent, specific SIRT5 inhibitor, increases the ammonia content in cells leading to autophagy and mitophagy, shows selective SIRT5 inhibition vs SIRT1-3.

    Physicochemical Properties

    M.Wt 618.687
    Formula C33H38N4O8
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-2-(((benzyloxy)carbonyl)amino)-5-(((S)-5-(((benzyloxy)carbonyl)amino)-6-oxo-6-(phenylamino)hexyl)amino)-5-oxopentanoic acid

    References

    1. Polletta L, et al. Autophagy. 2015;11(2):253-70.

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