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Chemical Structure : MCB-613
CAS No.: 1162656-22-5
Catalog No.: PC-45661Not For Human Use, Lab Use Only.
MCB-613 is a potent steroid receptor coactivator (SRC1, SRC2 and SRC3) stimulator.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $152 | In stock | |
| 25 mg | $240 | In stock | |
| 50 mg | $360 | In stock | |
| 100 mg | $520 | In stock |
Bulk size, bulk discount!
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MCB-613 is a potent steroid receptor coactivator (SRC1, SRC2 and SRC3) stimulator.
MCB-613 super-stimulates SRCs' transcriptional activity, increases SRCs' interactions with other coactivators and markedly induces ER stress coupled to the generation of ROS.
MCB-613 causes rapid and selective depletion of p53-R175H protein via an ubiquitin dependent lysosome-mediated pathway, inhibits tumor growth in vivo.
| M.Wt | 304.3856 | |
| Formula | C20H20N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: 10 mg/mL |
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| Chemical Name/SMILES |
Cyclohexanone, 4-ethyl-2,6-bis(3-pyridinylmethylene)-, (2E,6E)- |
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1. Wang L, et al. Cancer Cell. 2015 Aug 10;28(2):240-52.
2. Lonard DM, et al. Clin Cancer Res. 2016 Nov 15;22(22):5403-5407.
3. Padmanabhan A, et al. Nat Commun. 2018 Mar 28;9(1):1270.
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