MEN 11270 | B2R antagonist | Probechem Biochemicals

Chemical Structure : MEN 11270

MEN 11270 (MEN-11270, MEN11270)

Catalog No.: PC-26630Not For Human Use, Lab Use Only.

MEN 11270 is a high affinity, selective peptide antagonist of type 2 bradykinin receptor (B2R) with pKi of 10.3, >10,000-fold selective over Kinin B1 receptor (B1R).

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Biological Activity

MEN 11270 is a high affinity, selective peptide antagonist of type 2 bradykinin receptor (B2R) with pKi of 10.3, >10,000-fold selective over Kinin B1 receptor (B1R).

Physicochemical Properties

M.Wt	1299.55
Formula	C60H90N20O11S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-(2S)-2,4-diaminobutanoyl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, (10→7)-lactam

References

1. Meini S, et al. J Pharmacol Exp Ther. 1999 Jun;289(3):1250-6.

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MEN 11270 (MEN-11270, MEN11270)

Biological Activity

Physicochemical Properties

References

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