| Cat. No. |
Product Name |
Information |
| PC-20273 |
FR-190997
B2R agonist
|
FR-190997 (FR190997) is a potent, nonpeptide bradykinin (BK) B2 receptor agonist binding IC50 of 1.5 nM (displaced [3H]-BK binding to B2 receptors in guinea-pig ileum membranes). |
| PC-47507 |
Bradykinin
Bradykinin receptor ligand
|
Bradykinin is a 9-amino acid peptide (Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg). |
| PC-45267 |
Icatibant
B2R antagonist
|
Icatibant (HOE 140, JE-049) is a potent, selective and specific antagonist of bradykinin B2 receptor (B2R) with IC50 and Ki of 1.07 nM and 0.798 nM respectively. |
| PC-26638 |
FR173657
B2R antagonist
|
FR173657 (FK-3657) is a potent, selective, orally active bradykinin B2 receptor (B2R) antagonist with IC50 of 0.56, 1.5, 2.9 nM for pig, rat, human B2 receptor respectively. |
| PC-26637 |
Deucrictibant
B2R antagonist
|
Deucrictibant (PHA-022121, PHA121) is a potent, selective and oral bradykinin B2 receptor (B2R) antagonist with Ki of 0.47 nM for recombinant human bradykinin B2 receptor. |
| PC-26636 |
NVP-SAA164
B1R antagonist
|
NVP-SAA164 is a potent, selective orally active nonpeptide bradykinin B1 receptor (B1R) antagonist with Ki of 8 nM, inhibits increases in intracellular calcium induced by desArg10kallidin (desArg10KD) with IC50 of 33 nM. |
| PC-26635 |
MK-0686
B1R antagonist
|
MK-0686 is a potent, selective nonpeptidic antagonist of bradykinin B(1) receptor antagonist. |
| PC-26634 |
Safotibant
B1R antagonist
|
Safotibant (LF22-0542) is a potent, selective nonpeptidic antagonist of kinin B1 receptor (BKB1R, B1R), with Ki of 0.35 and 6.5 nM, for human and mouse BKB1R, respectively. |
| PC-26633 |
Fulimetibant
B1R antagonist
|
Fulimetibant is a potent, selective Bradykinin B1 receptor (B1R) antagonist. |
| PC-26632 |
Anatibant
B2R antagonist
|
Anatibant (LF 16-0687, XY-2405) is a potent, selective non-peptide bradykinin B2 receptor (B2R) antagonist with 0.67 nM, 1.74 nM and 1.37 nM for human, rat and guinea-pig recombinant B2 receptor respectively. |
| PC-26631 |
Fasitibant
B2R antagonist
|
Fasitibant (MEN16132) is a potent, selective, nonpeptide antagonist of type 2 bradykinin receptor (B2R) with pIC50 of 10.5 for [3H]-BK binding in mouse lung. |
| PC-26630 |
MEN 11270
B2R antagonist
|
MEN 11270 is a high affinity, selective peptide antagonist of type 2 bradykinin receptor (B2R) with pKi of 10.3, >10,000-fold selective over Kinin B1 receptor (B1R). |
