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Chemical Structure : MI-136
CAS No.: 1628316-74-4
Catalog No.: PC-45602Not For Human Use, Lab Use Only.
A potent Menin-MLL interaction inhibitor with IC50 of 31 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | $1680 | In stock |
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A potent Menin-MLL interaction inhibitor with IC50 of 31 nM; demonstrates potent inhibitory activity and strong binding affinity to menin.
| M.Wt | 470.5132 | |
| Formula | C23H21F3N6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 31 mg/mL |
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| Chemical Name/SMILES |
1H-Indole-2-carbonitrile, 5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]- |
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1. Borkin D, et al. J Med Chem. 2016 Feb 11;59(3):892-913.
2. Borkin D, et al. Cancer Cell. 2015 Apr 13;27(4):589-602.
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