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Chemical Structure : MID-1
Catalog No.: PC-35530Not For Human Use, Lab Use Only.
MID-1 (ChemBridge5655896) is a specific small molecule MG53-IRS-1 interaction disruptor (MID), but not MG53-FAK and-Cav-3 interaction.
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MID-1 (ChemBridge5655896) is a specific small molecule MG53-IRS-1 interaction disruptor (MID), but not MG53-FAK and-Cav-3 interaction; increases the IRS-1 protein level in C2C12 myotubes, abrogates MG53-induced IRS-1 ubiquitination and degradation; potentially sensitizes insulin signaling with an elevated level of IRS-1 in skeletal muscle, enhances C2C12 myogenesis.
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| Appearance | Solid | |
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10 mM in DMSO |
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1. Lee H, et al. J Biol Chem. 2016 Dec 23;291(52):26627-26635.
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