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MIF-IN-3bb

Chemical Structure : MIF-IN-3bb

CAS No.: 1663475-35-1

MIF-IN-3bb

Catalog No.: PC-63120Not For Human Use, Lab Use Only.

MIF-IN-3bb is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 57 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MIF-IN-3bb is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with Ki of 57 nM.
    MIF-IN-3bb displays >1000-fold more active than the well-studied (R)-ISO-1 and more than 200-fold more active than the chromen-4-one Orita-13.

    Physicochemical Properties

    M.Wt 442.406
    Formula C24H15FN4O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3-((2-(1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl)quinolin-5-yl)oxy)benzoic acid

    References

    1. Dziedzic P, et al. J Am Chem Soc. 2015 Mar 4;137(8):2996-3003.

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