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MIN-117

Chemical Structure : MIN-117

CAS No.: 310392-93-9

MIN-117 (WF-516;WF 516;MIN 117)

Catalog No.: PC-61106Not For Human Use, Lab Use Only.

A small molecule 5-HT1A and 5-HT2A receptor antagonist and inhibitor of serotonin and dopamine reuptake, also possess affinity for the α1A- and α1B-adrenergic receptors..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A small molecule 5-HT1A and 5-HT2A receptor antagonist and inhibitor of serotonin and dopamine reuptake, also possess affinity for the α1A- and α1B-adrenergic receptors.

Depression

Phase 2 Clinical

Physicochemical Properties

M.Wt 538.85
Formula C25H26Cl3N3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S)-1-[4-(3,4-dichlorophenyl)piperidin-1-yl]-3-[2-(5-methyl-1,3,4-oxadiazol-2-yl)benzo[b]furan-4-yloxy]propan-2-ol monohydrochloride

References

1. El Mansari M, et al. Naunyn Schmiedebergs Arch Pharmacol. 2008 Jan;376(5):351-61.

2. Saijo T, et al. PLoS One. 2012;7(8):e42589. doi: 10.1371/journal.pone.0042589.

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