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Chemical Structure : MJN110
CAS No.: 1438416-21-7
Catalog No.: PC-60707Not For Human Use, Lab Use Only.
MJN110 (MJN-110) is a potent, selective, and orally active MAGL inhibitor with IC50 of 2.1 nM (2-AG hydrolysis).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $158 | In stock | |
| 50 mg | $248 | In stock | |
| 100 mg | Get quote | ||
| 200 mg | Get quote | ||
| 1 g | Get quote |
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MJN110 (MJN-110) is a potent, selective, and orally active MAGL inhibitor with IC50 of 2.1 nM (2-AG hydrolysis).
MJN110 wekaly inhibits ABHD6, with excellent selectivity over FAAH and other serine hydrolases.
MJN110 inactivates hMAGL with IC50 of 9.1 nM, attenuates established mechanical allodynia in rat model of diabetic neuropathy.
| M.Wt | 462.327 | |
| Formula | C22H21Cl2N3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2,5-dioxopyrrolidin-1-yl 4-(bis(4-chlorophenyl)methyl)piperazine-1-carboxylat |
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1. Niphakis MJ, et al. ACS Chem Neurosci. 2013 Sep 18;4(9):1322-32.
2. Parker LA, et al. Psychopharmacology (Berl). 2015 Feb;232(3):583-93.
3. Ignatowska-Jankowska B, J Pharmacol Exp Ther. 2015 May;353(2):424-32. et al.
4. Wilkerson JL, et al. J Pharmacol Exp Ther. 2016 Apr;357(1):145-56.
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