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Chemical Structure : ML 086
Catalog No.: PC-62547Not For Human Use, Lab Use Only.
ML 086 is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM).
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ML 086 (ML086) is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM).
ML 086 is a useful chemical tool to examine the functional role of this enzyme in skeletal mineralization and soft tissue ossification abnormalities.
| M.Wt | 298.36 | |
| Formula | C16H14N2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Stonich D, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
2. Bravo Y, et al. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4308-11.
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