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Chemical Structure : ML239
CAS No.: 1378872-36-6
Catalog No.: PC-62221Not For Human Use, Lab Use Only.
ML239 is a selective small molecule inhibitor of breast cancer stem cells with IC50 of 1.18 uM, displays >23-fold selective inhibition of the breast CSC-like cell line over the isogenic control cell line.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $65 | In stock | |
| 25 mg | $155 | In stock | |
| 50 mg | $275 | In stock | |
| 100 mg | $495 | In stock | |
| 500 mg | Get quote |
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ML239 is a selective small molecule inhibitor of breast cancer stem cells (CSCs) with IC50 of 1.18 uM, displays >23-fold selective inhibition of the breast CSC-like cell line over the isogenic control cell line; alters the expression of genes in the MAPK, NF-κB, and inflammatory cytokine pathways; most likely acts through activation of fatty acid desaturase 2 (FADS2).
| M.Wt | 346.592 | |
| Formula | C13H10Cl3N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-(2,4,6-trichlorophenoxy)-acetic acid, (2E)-2-(1H-pyrrol-2-ylmethylene)hydrazide |
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1. Rees MG, et al. Nat Chem Biol. 2016 Feb;12(2):109-16.
2. Carmody LC, et al. J Biomol Screen. 2012 Oct;17(9):1204-10.
3. Germain AR, et al. Bioorg Med Chem Lett. 2012 May 15;22(10):3571-4.
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