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ML377

Chemical Structure : ML377

CAS No.:

ML377 (MLS 0472732)

Catalog No.: PC-62119Not For Human Use, Lab Use Only.

ML377 (MLS 0472732) is a small molecule probe that selectively inhibits TAG (Triacylglyceride) accumulation with an IC50 of 1.1 uM, show >45-fold selectivity versus DGAT inhibition and cytotoxicity..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ML377 (MLS 0472732) is a small molecule probe that selectively inhibits TAG (Triacylglyceride) accumulation with an IC50 of 1.1 uM, show >45-fold selectivity versus DGAT inhibition and cytotoxicity.

Physicochemical Properties

M.Wt 440.503
Formula C26H24N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-2-(2-ethoxyethyl)-3-oxoiso-indoline-4-carboxamide

References

1. Hershberger PM, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

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