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Chemical Structure : ML379
Catalog No.: PC-62117Not For Human Use, Lab Use Only.
ML379 (CID71576758) is a potent, selective TP53 mutant cancer cells inhibitor with IC50 of 13 nM in sensitive HeLa cells (TP53 mutant).
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ML379 (CID71576758) is a potent, selective TP53 mutant cancer cells inhibitor with IC50 of 13 nM in sensitive HeLa cells (TP53 mutant).
ML379 displays >1,000-fold selectivity over insensitive A549 cells (TP53 wild type).
ML379 displays low nM activity in a larger panel of TP53 mutant cell lines.
| M.Wt | 273.33 | |
| Formula | C15H19N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lewis TA, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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