Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : ML387
Catalog No.: PC-62124Not For Human Use, Lab Use Only.
ML387 (CID3474778) is a potent, selective NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with IC50 of 19 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
ML387 (CID3474778) is a potent, selective NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with IC50 of 19 nM; dispalys 71-fold selectivity versus ALDH1A1, and >1,000 fold versus LDHA, LDHB, rGAPDH, and HSD17B4; potently promotes PGE2 production in both A549 lung cancer and LNCaP prostate cancer cells.
| M.Wt | 449.43 | |
| Formula | C22H22F3N3O4 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Duveau DY, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
