Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : ML388
Catalog No.: PC-62123Not For Human Use, Lab Use Only.
ML388 is a potent, selective NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with IC50 of 34 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
ML388 is a potent, selective NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with IC50 of 34 nM; dispalys 71-fold selectivity versus ALDH1A1, and >1,000 fold versus LDHA, LDHB, GAPDH, and HSD17B4; potently promotes PGE2 production in both A549 lung cancer and LNCaP prostate cancer cells.
| M.Wt | 434.463 | |
| Formula | C22H25F3N4O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Duveau DY, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
