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Chemical Structure : ML389
Catalog No.: PC-62116Not For Human Use, Lab Use Only.
ML389 is a highly potent, selective vasopressin receptor 1a (V1a-R) antagonist with IC50 of 40 nM.
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ML389 is a highly potent, selective vasopressin receptor 1a (V1a-R) antagonist with IC50 of 40 nM; dispalys >1,250-fold selectivity over V1b-R, V2-R, and OXTR; has good brain penetration, no significant activity at four human cytochrome P450 subtypes, high binding for human and rodent plasma protein, and an encouraging in vivo pharmacokinetic profile in mice.
| M.Wt | 404.33 | |
| Formula | C21H23Cl2N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Mittapalli G, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].
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