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Chemical Structure : MS-L6
Catalog No.: PC-22285Not For Human Use, Lab Use Only.
MS-L6 is a novel small molecule OXPHOS inhibitor, exerts dual mitochondrial effects: mitochondrial electron transport chain complexe ETC-I inhibition and uncoupling of OXPHOS.
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MS-L6 is a novel small molecule OXPHOS inhibitor, exerts dual mitochondrial effects: mitochondrial electron transport chain complexe ETC-I inhibition and uncoupling of OXPHOS.
MS-L6 inhibits respiration of hepatocytes and cancer cells via ETC-I.
MS-L6 decreases ΔΨm in rat liver mitochondria and cancer cells.
MS-L6 exhibits mild cytotoxic effects on several cancer cell lines and remarkably inhibits tumor growth in preclinical mouse cancer models without toxicity.
| M.Wt | 386.58 | |
| Formula | C20H26N4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Al Assi A, et al. Cell Death Dis. 2024 May 2;15(5):311.
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