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Chemical Structure : MS7972
CAS No.: 352553-42-5
Catalog No.: PC-62280Not For Human Use, Lab Use Only.
MS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association, completely blocks CBP BRD/p53-AcK382 interactions at 50 uM, results in loss of p53 phosphorylation at Ser15 as well as acetylation at Lys382.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $148 | In stock | |
| 10 mg | $228 | In stock | |
| 25 mg | $388 | In stock | |
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MS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association, completely blocks CBP BRD/p53-AcK382 interactions at 50 uM, results in loss of p53 phosphorylation at Ser15 as well as acetylation at Lys382.
MS7972 causes a dramatic decrease of the doxorubicin-induced p53 increase in U2OS cells.
| M.Wt | 227.263 | |
| Formula | C14H13NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
9-Acetyl-3,4-dihydro-2H-carbazol-1-one |
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1. Sachchidanand, et al. Chem Biol. 2006 Jan;13(1):81-90.
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