Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : MSI-1436
Catalog No.: PC-42921Not For Human Use, Lab Use Only.
MSI-1436 (Trodusquemine) is an non-competitive, allosteric inhibitor of PTP1B with Ki of 0.6 uM for PTP1B 1-405.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
MSI-1436 (Trodusquemine) is an non-competitive, allosteric inhibitor of PTP1B with Ki of 0.6 uM for PTP1B 1-405.
MSI-1436 antagonizes HER2 signaling, inhibits tumorigenesis in xenografts and abrogates metastasis in the NDL2 mouse model of breast cancer.
| M.Wt | 685.0564 | |
| Formula | C37H72N4O5S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Krishnan N, et al. Nat Chem Biol. 2014 Jul;10(7):558-66.
2. Qin Z, et al. Biochem Biophys Res Commun. 2015 Feb 27;458(1):21-7.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
