MU1656 |CAS 2768008-84-8 Probechem Biochemicals

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Chemical Structure : MU1656

MU1656 (MU 1656)

Catalog No.: PC-38010Not For Human Use, Lab Use Only.

MU1656 (MU 1656 ) is a potent, highly selective inhibitor of histone methyltransferase DOT1L with IC50 of 2 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MU1656 (MU 1656 ) is a potent, highly selective inhibitor of histone methyltransferase DOT1L with IC50 of 2 nM.
MU1656 displays highly selectively against a panel of 37 methyltransferases.
MU1656 is more metabolically stable and significantly less toxic in vivo than pinometostat.

Physicochemical Properties

M.Wt	559.759
Formula	C32H45N7O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,2S,3S,5R)-3-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)cyclopentane-1,2-diol

References

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MU1656 (MU 1656)

Biological Activity

Physicochemical Properties

References

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