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Methazolamide

Chemical Structure : Methazolamide

CAS No.: 554-57-4

Methazolamide (L584601)

Catalog No.: PC-24457Not For Human Use, Lab Use Only.

Methazolamide (L584601) is a potent, BBB-penatrable and orally active carbonic anhydrase inhibitor with Ki of 14 nM for human carbonic anhydrase II (CA II).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Methazolamide (L584601) is a potent, BBB-penatrable and orally active carbonic anhydrase inhibitor with Ki of 14 nM for human carbonic anhydrase II (CA II).

Physicochemical Properties

M.Wt 236.26
Formula C5H8N4O3S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(3-Methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide

References

1. Li M, et al. Sci Rep. 2016 Oct 12;6:35055.

2. Alterio V., et al. J. Enzym. Inhib. Med. Chem. 2018;33:151–157.

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