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Chemical Structure : Methyl-β-cyclodextrin
CAS No.: 128446-36-6
Catalog No.: PC-42392Not For Human Use, Lab Use Only.
A cholesterol depleting agent that shows antitumor activity both in vitro and in vivo.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 g | $56 | In stock | |
| 10 g | $80 | In stock | |
| 25 g | $152 | In stock | |
| 50 g | $192 | In stock |
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A cholesterol depleting agent that shows antitumor activity both in vitro and in vivo; induces caspase-dependent apoptosis in PEL cells via cholesterol depletion from the plasma membrane; significantly potentiates the activity of doxorubicin used alone on both sensitive and multidrug-resistant cell lines, and enhances the susceptibility of human breast cancer cells to carboplatin and 5-FU.
| M.Wt | N/A | |
| Formula | 1310 (Average) | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 31 mg/mL |
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| Chemical Name/SMILES |
β-Cyclodextrin, methyl ethers |
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1. Mahammad S, et al. Methods Mol Biol. 2015;1232:91-102.
2. Gotoh K, et al. Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):285-9.
3. Grosse PY, et al. Cancer Chemother Pharmacol. 1997;40(6):489-94.
4. Upadhyay AK, et al. Toxicol Appl Pharmacol. 2006 Oct 15;216(2):177-85.
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