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Chemical Structure : Migrastatin
Catalog No.: PC-70248Not For Human Use, Lab Use Only.
A biologically active natural product isolated from Streptomyces that has been shown to inhibit tumor cell migration.
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A biologically active natural product isolated from Streptomyces that has been shown to inhibit tumor cell migration; potently inhibits cancer metastasis in a murine breast tumor model, blocks Rac activation, lamellipodia formation, and cell migration, interferes with the invasion step of the metastatic process.
| M.Wt | 489.6 | |
| Formula | C27H39NO7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Shan D, et al. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3772-6.
2. Chen L, et al. Nature. 2010 Apr 15;464(7291):1062-6.
3. Lecomte N, et al. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15074-8.
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