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Chemical Structure : Mirabegron
CAS No.: 223673-61-8
Catalog No.: PC-21196Not For Human Use, Lab Use Only.
Mirabegron (YM178) is a potent, selective selective β3-adrenoceptor agonist with EC50 of 22.4 nM.
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Mirabegron (YM178) is a potent, selective selective β3-adrenoceptor agonist with EC50 of 22.4 nM.
Mirabegron (YM178) displays no activity against human beta1- and beta2-ARs.
Mirabegron (YM178) exhibited relaxant effects of YM178 were evaluated in rats and humans bladder strips precontracted with carbachol (CCh.
Mirabegron (YM178) (3 mg/kg, i.v.) decreased the frequency of rhythmic bladder contraction induced by intravesical filling with saline without suppressing its amplitude in anesthetized rats.
| M.Wt | 396.51 | |
| Formula | C21H24N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]-ethyl} acetanilide |
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1. Takasu T, et al. J Pharmacol Exp Ther. 2007 May;321(2):642-7.
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