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Chemical Structure : MitoBloCK-11
Catalog No.: PC-35923Not For Human Use, Lab Use Only.
MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20.
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MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20.
MitoBloCK-11 inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
| M.Wt | 434.264 | |
| Formula | C17H12BrN3O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Conti, M. (2018). Small Molecule Probes of Mitochondrial Translocases Elucidate PINK1 Trafficking in PINK1/Parkin Regulated Mitophagy. UCLA.
2. Miyata N, et al. J Biol Chem. 2017 Mar 31;292(13):5429-5442.
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