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Mosapride

Chemical Structure : Mosapride

CAS No.: 112885-41-3

Mosapride (AS-4370, AS4370)

Catalog No.: PC-27525Not For Human Use, Lab Use Only.

Mosapride (AS-4370) is a gastroprokinetic agent that acts as a selective 5-HT4 agonist, has concentration-dependent inhibitory effect on Kv4.3.

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25 mg $48 In stock
50 mg $78 In stock
100 mg $118 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Mosapride (AS-4370) is a gastroprokinetic agent that acts as a selective 5-HT4 agonist, has concentration-dependent inhibitory effect on Kv4.3.
Mosapride accelerates gastric emptying throughout the whole of the gastrointestinal tract invivo, and is used for the treatment of gastritis, gastro-oesophageal reflux disease, functional dyspepsia and irritable bowel syndrome.

Physicochemical Properties

M.Wt 421.90
Formula C21H25ClFN3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)morpholin-2-yl)methyl)benzamide

References

1. Kato S, et al. J Med Chem. 1991 Feb;34(2):616-24.

2. Yoshida N, et al. J Pharmacol Exp Ther. 1991 May;257(2):781-7.

3. Sakashita M, et al. Arzneimittelforschung. 1993 Aug;43(8):859-63.

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