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Mosedipimod

Chemical Structure : Mosedipimod

CAS No.: 221139-79-3

Mosedipimod (EC-18;1-palmitoyl-2-linoleoyl-3-acetylglycerol)

Catalog No.: PC-35759Not For Human Use, Lab Use Only.

Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro; attenuates the asthmatic response in an aluminum hydroxide/ovalbumin-induced model of asthma, inhibits hematogenous metastasis of KIGB-5 biliary cancer cell in hamster model.

Other Indication

Phase 2 Clinical

Physicochemical Properties

M.Wt 634.98
Formula C39H70O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-1-acetoxy-3-(palmitoyloxy)propan-2-yl (9Z,12Z)-octadeca-9,12-dienoate

References

1. Yoon SY, et al. Immune Netw. 2015 Apr;15(2):100-9.

2. Shin IS, et al. Int Immunopharmacol. 2016 Jan;30:62-68.

3. Shin IS, et al. Int Immunopharmacol. 2014 Jan;18(1):116-23.

4. Kim MH, et al. J Korean Med Sci. 2009 Jun;24(3):474-80.

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