MrgX1 modulator 8e

Chemical Structure : MrgX1 modulator 8e

Catalog No.: PC-38501Not For Human Use, Lab Use Only.

MrgX1 inhibitor 8e is a potent, allosteric modulator of MrgX1 with EC50 of 13 nM, showed improved potency and microsomal stability than ML382.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MrgX1 inhibitor 8e is a potent, allosteric modulator of MrgX1 with EC50 of 13 nM, showed improved potency and microsomal stability than ML382.

M.Wt	396.409
Formula	C18H18F2N2O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(cyclopropanesulfonamido)-N-(2-ethoxy-5-fluorophenyl)-5-fluorobenzamide

1. Swagat Sharma, et al. ACS Med. Chem. Lett. 2022.