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Mutated EGFR-IN-1

Chemical Structure : Mutated EGFR-IN-1

CAS No.: 1421372-66-8

Mutated EGFR-IN-1

Catalog No.: PC-45995Not For Human Use, Lab Use Only.

A des acryl analogue of AZD9291 that is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A des acryl analogue of AZD9291 that is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant.

Physicochemical Properties

M.Wt 445.5599
Formula C25H31N7O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 75 mg/mL

Chemical Name/SMILES

1,2,4-Benzenetriamine, N1-[2-(dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-

References

1. Patent WO 2013014448 A1.

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