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Chemical Structure : NAH-C3-GPKK
Catalog No.: PC-72717Not For Human Use, Lab Use Only.
NAH-C3-GPKK is a potent, selective protein N-terminal methyltransferase 1 (NTMT1) bisubstrate inhibitor with Kiapp of 7 nM in endogenous proteomes.
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NAH-C3-GPKK is a potent, selective protein N-terminal methyltransferase 1 (NTMT1) bisubstrate inhibitor with Kiapp of 7 nM in endogenous proteomes.
NAH-C3-GPKK also potently inhibit a methyltransferase complex HemK2-Trm112 (also known as KMT9-Trm112, IC50=0.3 uM).
NAH-C3-GPKK is the first potent inhibitor for HemK2/KMT9.
| M.Wt | 835.965 | |
| Formula | C36H61N13O10 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Dongxing Chen, et al. ACS Chem Biol. 2021 Jul 16;16(7):1234-1242.
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