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Chemical Structure : NAMPT activator (NAT)
CAS No.: 831243-31-3
Catalog No.: PC-38439Not For Human Use, Lab Use Only.
NAMPT activator (NAT) is a potent, small molecule activator of nicotinamide phosphoribosyltransferase (NAMPT) with ITC KD of 500 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | Get quote |
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NAMPT activator (NAT) is a potent, small molecule activator of nicotinamide phosphoribosyltransferase (NAMPT) with ITC KD of 500 nM.
NAMPT activator (NAT) markedly increased the catalytic activity (Vmax) of NAMPT with higher Michaelis constants (Km) for both substrates, NAM, and PRPP.
The stoichiometry analysis revealed that NAT bound to NAMPT at a 1:1 ratio, NAT may function as a reversible activator during the kinetic assay, and has no effect on NMNAT1 enzyme activity.
| M.Wt | 299.370 | |
| Formula | C18H21NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-(2-(tert-butyl)phenoxy)-N-(4-hydroxyphenyl)acetamide |
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1. Hong Yao, et al. Cell Research (2022) 0:1-15.
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