Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : NCATS-SM4487
Catalog No.: PC-72398Not For Human Use, Lab Use Only.
NCATS-SM4487 is a potent, small molecule inhibitor galactokinase (GALK1) with IC50 of 50 nM (hGALK1).
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
NCATS-SM4487 is a potent, small molecule inhibitor galactokinase (GALK1) with IC50 of 50 nM (hGALK1).
NCATS-SM4487 prevents galactose-1 phosphate (gal-1P) accumulation in patient-derived cells at low micromolar concentrations and have pharmacokinetic properties suitable for evaluation in rodent models of galactosemia.
| M.Wt | 522.969 | |
| Formula | C25H24ClFN8O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
|
|
1. Li Liu, et al. J Med Chem. 2021 Sep 23;64(18):13551-13571.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
