NCGC00138783

Chemical Structure : NCGC00138783

Catalog No.: PC-26940Not For Human Use, Lab Use Only.

NCGC00138783 is a selective inhibitor targeting CD47/SIRPα axis with IC50 of 50 µM, directly blocks the interaction between CD47 and SIRPα.

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Biological Activity

NCGC00138783 is a selective inhibitor targeting CD47/SIRPα axis with IC50 of 50 µM, directly blocks the interaction between CD47 and SIRPα.

M.Wt	503.60
Formula	C26H26FN7OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Butanamide, 2-[[2-[2-(3,5-dimethyl-1H-pyrazol-4-yl)ethyl][1,2,4]triazolo[1,5-c]quinazolin-5-yl]thio]-N-(4-fluorophenyl)-

1. Bo Huang, et al. Comput Struct Biotechnol J. 2021 Oct 1;19:5494-5503.