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Chemical Structure : NF-56-EJ40
CAS No.: 2380230-73-7
Catalog No.: PC-72374Not For Human Use, Lab Use Only.
NF-56-EJ40 is a highly potent, human-selective antagonist of SUCNR1 (GPR91) with IC50 of 25 nM and Ki of 33 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $228 | In stock | |
| 10 mg | $388 | In stock | |
| 25 mg | $588 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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NF-56-EJ40 is a highly potent, human-selective antagonist of SUCNR1 (GPR91) with IC50 of 25 nM and Ki of 33 nM.
NF-56-EJ40 is highly selective for human SUCNR1 and showed almost no activity towards rat SUCNR1.
NF-56-EJ40 significantly interrupt succinate/IL-1β signal in HUVECs and macrophages.
| M.Wt | 443.54 | |
| Formula | C27H29N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2-(2-(4'-((4-Methylpiperazin-1-yl)methyl)-[1,1'-biphenyl]-3-carboxamido)phenyl)acetic acid |
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1. Matthias Haffke, et al. Nature. 2019 Oct;574(7779):581-585.
2. Jingwen Xu, et al. Front Immunol. 2022 Feb 22;13:817572.
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