NFAT inhibitor 14

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Chemical Structure : NFAT inhibitor 14

Catalog No.: PC-28453Not For Human Use, Lab Use Only.

NFAT inhibitor 14 is a small-molecule calcineurin-nuclear factor of activated T cells (NFAT) signaling inhibitor, inhibits the nuclear translocation and transcriptional activity of both NFATc1 and NFATc2, suppresses NFAT-dependent cytokine production, and shows cellular immunosuppressive activities.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NFAT inhibitor 14 is a small-molecule calcineurin-nuclear factor of activated T cells (NFAT) signaling inhibitor, inhibits the nuclear translocation and transcriptional activity of both NFATc1 and NFATc2, suppresses NFAT-dependent cytokine production, and shows cellular immunosuppressive activities.

Physicochemical Properties

M.Wt	384.43
Formula	C20H17FN2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(N-Benzylsulfamoyl)−4-fluoro-N-phenylbenzamide

References

1. Hong JE, et al. Arch Pharm Res. 2026 Oct 9. doi: 10.1007/s12272-026-01638-5.

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