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Chemical Structure : NH4-13
Catalog No.: PC-72769Not For Human Use, Lab Use Only.
NH4-13 is a potent, SIRT2-selective inhibitor with IC50 of 87 nM, shows no inhibition against SIRT1/3/5/6 (IC50>50 uM).
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NH4-13 is a potent, SIRT2-selective inhibitor with IC50 of 87 nM, shows no inhibition against SIRT1/3/5/6 (IC50>50 uM).
NH4-13 (30 mg/kg) significantly impaired tumor growth in HCT-116 tumor xenograft.
| M.Wt | 719.808 | |
| Formula | C33H58IN3O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jun Young Hong, et al. ACS Chem Biol. 2021 Jul 16;16(7):1266-1275.
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