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Chemical Structure : NH4-6
Catalog No.: PC-72770Not For Human Use, Lab Use Only.
NH4-6 is a potent pan SIRT1-3 inhibitor with IC50 of 3.0/0.032/2.3 uM for SIRT1/2/3, respectively.
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NH4-6 is a potent, selective pan SIRT1-3 inhibitor with IC50 of 3.0/0.032/2.3 uM for SIRT1/2/3, respectively.
NH4-6 does not inhibits SIRT5 and SIRT6.
NH4-6 (30 mg/kg) significantly impaired tumor growth in HCT-116 tumor xenograft.
| M.Wt | 718.824 | |
| Formula | C33H59IN4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jun Young Hong, et al. ACS Chem Biol. 2021 Jul 16;16(7):1266-1275.
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