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Chemical Structure : NKG2D inhibitor 4e
Catalog No.: PC-21268Not For Human Use, Lab Use Only.
NKG2D inhibitor 4e is a small-molecule protein-protein interaction inhibitor for NKG2D with IC50 of 2.2 uM, disrupts the interaction between NKG2D and multiple protein ligands through allosteric modulation of the NKG2D receptor dimer/ligand interface.
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NKG2D inhibitor 4e is a small-molecule protein-protein interaction inhibitor for NKG2D with IC50 of 0.1 uM, disrupts the interaction between NKG2D and multiple protein ligands through allosteric modulation of the NKG2D receptor dimer/ligand interface.
| M.Wt | 455.48 | |
| Formula | C25H24F3N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Thompson AA, et al. Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2216342120.
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