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NM107

Chemical Structure : NM107

CAS No.: 20724-73-6

NM107 (2'-C-Methylcytidine;NM-107;Valopicitabine)

Catalog No.: PC-42605Not For Human Use, Lab Use Only.

NM107 (Valopicitabine) is a nucleoside inhibitor of HCV NS5B polymerase with EC50 of 1.23 uM against HCV 1b replicon cells.

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Biological Activity

NM107 (Valopicitabine) is a nucleoside inhibitor of HCV NS5B polymerase with EC50 of 1.23 uM against HCV 1b replicon cells.
NM107 (Valopicitabine) is the active component of NM283.

Physicochemical Properties

M.Wt 257.2432
Formula C10H15N3O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Cytidine, 2'-C-methyl-

References

1. Gardelli C, et al. J Med Chem. 2009 Sep 10;52(17):5394-407.

2. McCown MF, et al. Antimicrob Agents Chemother. 2008 May;52(5):1604-12.

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