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NSC207895

Chemical Structure : NSC207895

CAS No.: 58131-57-0

NSC207895 (XI-006)

Catalog No.: PC-26088Not For Human Use, Lab Use Only.

NSC207895 (XI-006) is a small-molecule inhibitor of MDMX (MDM4) and p53 activator, activates p53 and induces apoptosis, inhibits MDMX expression in cancer cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

NSC207895 (XI-006) is a small-molecule inhibitor of MDMX (MDM4) and p53 activator, activates p53 and induces apoptosis, inhibits MDMX expression in cancer cells.

Physicochemical Properties

M.Wt 279.26
Formula C11H13N5O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,1,3-Benzoxadiazole, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide

References

1. Woodfield SE, et al. Sci Rep. 2021 Feb 3;11(1):2967.

2. Wang H, et al. Mol Cancer Ther. 2011 Jan;10(1):69-79.

3. Pishas KI, et al. Sci Rep. 2015 Jun 22;5:11465.

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